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Publications

Joint Publications

1.“Multivalent glycoconjugates as anti-pathogenic agents“ A. Bernardi, J. Jiménez-Barbero, et al.,  Chem. Soc. Rev., 2013, DOI:10.1039/C2CS35408J.

2.“Tetrafluorination of sugars as strategy for enhancing protein-carbohydrate affinity: application to UDP-galactopyranose inhibition” N’Go, S. Golten, Ana Ardá, J. Cañada, J. Jiménez-Barbero, B. Linclau, and S.P. Vincent, Chem. Eur. J., 2013, in press.

3.Tanc, M.; Carta, F.; Bozdag, M.; Scozzafava, A.; Supuran, C.T.; 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors, Bioorg. Med. Chem., 2013, 15, 4502.

4. Aksu, K.; Nar, M.; Tanc, M.; Vullo, D.; Gülçin, #.; Göksu, S.; Tümer, F.; Supuran, C. T. Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine, Bioorg. Med. Chem., 2013, 11, 2925.

5. Leitans, J.; Sprudza, A.; Tanc, M.; Vozny, I.;Zalubovskis, I. Tars, K.; Supuran, C.T. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies, Bioorg. Med. Chem., 2013, 17, 5130.

6. Sethi, K K.; Verma, S.M.; Tanç, M.; Carta, F.; Supuran, C. T.; Carbonic Anhydrase Inhibitors: Synthesis and Inhibition of the cytosolic mammalian carbonic anhydrase isoforms I, II and VII with benzene sulfonamides incorporating 4,5,6,7-tetrachlorophthalic anhydride moiety, Bioorg. Med. Chem., 2013, 17, 5168

7. Ulus, R.; Yesildag, I.; Tanç, M.; Bülbül, M.; Kaya, M.; Supuran, C. T.; Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII, Bioorg. Med. Chem., 2013, 18, 5799

8. Sethi, K K.; Vullo, D.; Verma, S.M; Tanç M.; Carta, F.; Supuran, C. T.; Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety Bioorg. Med. Chem., 2013, 19, 5973

9. VILLALOBO, A., GARCÍA-PALMERO, I., STATEVA, S. R., & JELLALI, K.: Targeting the calmodulin-regulated ErbB/Grb7 in cancer therapy, J. Pharm. Pharmaceut. Sci., 2013, 16, 52-64.

10. Sethi, K K.; Verma, S.M.; Tanc, M.;; Purper, G.; Calafato, G.; Carta, F.; Supuran, C. T., Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties, Bioorg. Med. Chem., 2014, 22(5), 1586.

11. Grandane, A.;Tanc, M.; Zalubovskis, R.; Supuran, C.T.; 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII, Bioorg. Med. Chem. Lett., 2014, 24(5),1256.

12.Grandane, A.; Tanc, M.; Zalubovskis, R.; Supuran, C.T.; Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII, Bioorg. Med. Chem., 2014, 22(5),1522.

13. Mihai Barboiu, Zineb Mouline, Mihaela Silion, Erol Liscandru, Bogdan C. Simonescu, Eugen Mahon and Mariana Pinteala, Multivalent Recognition of Concavalin A by {Mo132}Glycoanocapsules-Toward Biomimetic Hybrid Multilayers, Chem. Eur. J., 2014, 20, 6678-6683.

14. Ruff, Y.; Garavini, V.; Giuseppone, N, Reversible Native Chemical Ligation: A Facile Access to Dynamic Covalent Peptides, J. Am. Chem. Soc. 2014, 136 (17), 6333–6339.

15. Luca Unione, Silvia Galante, Dolores Díaz, F. Javier Cañada and Jesús Jiménez-Barbero, NMR and molecular recognition. The application of ligand-based NMR methods to monitor molecular interactions, Med. Chem. Commun., 2014,5, 1280-1289.

16. Bixue Xu, Luca Unione, Joao Sardinha, Shaoping Wu, Mélanie Ethève-Quelquejeu, Amelia Pilar Rauter, Yves Blériot, Yongmin Zhang, Sonsoles Martín-Santamaría, Dolores Díaz, Jesus Jimenez-Barbero and Matthieu Sollogoub, gem-Difluorocarbadisaccharides: Restoring the exo-Anomeric Effect, Ange. Chem. Int. Ed., 2014, 53, 36, 9597-9602.

17. Abdelrahim, M.Y.M.; Tanc, M.; Winum, J.; Supuran, C.T.; Barboiu, M, Dominant behaviours in the expression of human carbonic anhydrase hCA I activity, Chem. Comm., 2014, 50 (59), 8043

18. Le Darz, A.; Mingot, A.; Bouazza, F.; Castelli, U.; Karam, O.; Tanc, M.; Supuran, C.T.; Thibaudeau, S, Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors, J. Enzyme Inhib. Med. Chem., 2014, 1

19. Tanc, M.; Carta, F.; Scozzafava, A.; Supuran, C.T, 6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA, JACS, XX, 2015, X

20. Boztaş, M.; Çetinkaya, Y.; Topal, M.; Gülçin, İ.; Menzek, A.; Şahin, E.; Tanc M.; Supuran, C. T., Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxy-bromophenol Derivatives Incorporating Cyclopropane Moieties, J. Med. Chem., 2015, 58(2), 640.

21.Tanc, M.; Carta, F.; Bozdag, M.; Scozzafava, A.; Supuran, C.T, α-Carbonic anhydrases possess thiesterase activity, Med. Chem. Lett., 2015.

22. S. El-Kirat-Chatel, A. Beaussart, S. Vincent, M. Abellán-Flos, P. Hols, P. N. Lipke, Y. F. Dufrêne, Forces in yeast flocculation, Nanoscale 2015, 7, 1760-1767.

23. Romina Catana, Mihail Barboiua*, Ioana Moleavinb, Lilia Climab, Alexandru Rotarub, Elena-Laura Ursub and Mariana Pintealab, Dynamic constitutional frameworks for DNA biomimetic recognition, Chem. Comm., 2015, 51, 2021-2024.

24.Silviya R. Stateva, Valentina Salas, Gustavo Benaim, Margarita Menéndez, Dolores Solís, Antonio Villalobo, Characterization of Phopsho-(Tyrosine) Mimetic Calmodulin Mutants, Plos one DOI: 10.1371, 2015.

25. L. Hu, F. Schaufelberger, B. J. J. Timmer, M. Abellán-Flos and O. Ramström, Constitutional Dynamic Chemistry, Kirk-Othmer Encyclopedia of Chemical Technology. Wiley, 2014, p1-25.


 

Organisation of or presentations at external specialist workshops and conferences by DYNANO partners:

Organization:

1. International research conference on “Supramolecular Approaches in Systems Chemistry” December 15-17, 2011, Strasbourg, France, N. Giuseppone

2. Dynamic Interactive Systems-toward natural selection of functions, Symposium “Open Problems in Systems Chemistry”, Montpellier, 23-25 01 2012. M Barboiu,

3. June 10-13, 2014, Stockholm, Sweden; Swedish National Meeting in Organic Chemistry (Organikerdagarna); In preparation

4. GLYCOPHARM-ITN meeting including a session “Women in science” October 2013, Dolores Solis

Participation or invited lectures :
1. M. Barboiu, Invited Lecture, Artificial Water Channels, Future Membranes and membrane Processes Symposium, Sponsored by WCU Program Department of Energy Engineering, Hanyang University, 19 August 2013, Seoul, Korea.

2. M. Barboiu, Rubbery Organic Frameworks-ROFs-Tuning the gaz-diffusion through dynameric membranes, Invited Lecture, World Congress on Chemical Engineering WCCE-2013 18-22 August, 2013, Seoul, Korea.

3. M. Barboiu, Invited Lecture, Water in confined media, water channels, 1ere ECOLE PRATIQUE D’ETE LABEX CHEMISYST – POLE CHIMIE BALARD, 1-6 juillet 2013, Ales, France

4. M. Barboiu, Y. Le Duc, A. Gilles, P. A. Cazade, M. Michau, Y. M. Legrand, A. van der Lee, B. Coasne, J. Post, T. Fyles, Artificial water channels: a primitive mimic of Gramicidin-A channel, Invited Lecture, North American Membrane Society NAMS-2013 10-13 06, 2013, Boise, USA.

5. G. Nasr, T. Macron, M. Barboiu, Rubbery Organic Frameworks-ROFs-Tuning the gaz-diffusion through dynameric membranes, Invited Lecture, North American Membrane Society NAMS-2013 meeting 10-13 June, 2013, Boise, USA.

6. M. Barboiu, Dynamic Constitutional Chemistry of Carbonic Anhydrase Inhibitors. Carbonic Anhydrase Frontiers Symposium, April 18-20, 2013, Montecatini, Italy.

7. M. Barboiu, Invited Lecture, Dynamic Interactive Systems-toward natural selection of functions, Membrane Material Platforms and Concepts for Energy, Environment, and Medical Applications, 2012 MRS Fall meeting, November 25-30, 2012, Hynes Convention Center - Boston, Massachusetts

8. M. Barboiu, Invited Lecture, Dynamic Interactive Systems-toward natural selection of functions, “French American Innovation Day seminar (FAID 2012), MIT, Bartos Theater, 29-30 November 2012 in Cambridge, Massachusetts

9. M. Barboiu, Plenary Lecture, Dynamic Interactive Systems-toward natural selection of functions, “Supramolecular Symposium: Dynamics and Adaptation”, 4-6 November 2012, Hangzhou, China.

10. M. Barboiu, Invited Lecture, G4-interactive systems and materials, “Conformational diversity and applications of G-quadruplexes“Hotel Antemare SPA, Sitges (Barcelona, Spain) from 6-8 th October 2012.

11. M. Barboiu, Plenary Lecture, Dynamic Interactive Systems-toward natural selection of functions 32nd Romanian Chemistry Conference, Calimanesti-Caciulata, Romania, 2-5-10-2012.

12. M. Barboiu, Invited Lecture, Imidazole Quartet - I4 -Water and Proton Dipolar Channels, Joint EMS-NAMS session, Euromembrane-2012 23-27 September, 2012, London, UK.

13. M. Barboiu, Invited Lecture, Dynamique de structuration de l’eau en milieu confiné, 1ere ECOLE PRATIQUE D’ETE LABEX CHEMISYST – POLE CHIMIE BALARD, 10-15 septembre 2012, Montpellier/Saint-Martin de Londres, France.

14. M. Barboiu on behalf of Prof. Cot, Invited Lecture Inorganic Membranes 20 years after, Honorary session: Founding fathers of inorganic membranes, International Conference on Inorganic membranes- ICIM2012, 9-13 July, 2012, Enschede , the Netherlands.

15. M. Barboiu, Plenary Lecture Dynamic Interactive Systems-toward natural selection of functions, Colloque Franco-Roumain de Chimie appliquée-COFROCA 2012, Bacau, Romania, 27-29 June, 2012.

16. M. Barboiu, Invited Lecture, Adaptive Responsive Membranes, Concepts and applications of stimuli responsive membranes, Summer Workshop, 20-22 June 2012, San Sebastian, Spain.

17. M. Barboiu, T. Macron and G. Nasr, Invited Lecture, Dynameric Membranes for Gas Separation: Achieving the Molecular Limit of Constitutional Gaz-Dynamer Interactions, North American Membrane Society NAMS-2012 meeting 10-13 June, 2012, New Orleans, USA.

18. Y.-M. Legrand, Y. Le Duc, M. Michau, A. Gilles, A. van der Lee, S. Tingry, M. Barboiu, Invited Lecture, Imidazole Quartet - I4 - Forming Water and Proton Dipolar Channels, North American Membrane Society NAMS-2012 meeting 10-13 June, 2012, New Orleans, USA.

19. M. Barboiu, Invited Lecture, Constitutional dynamic multivalent biomimetic systems, Rencontres en Chimie Organique Biologique, RECOB14, Aussois, 18-22 March 2012.

20. M. Barboiu, Invited Lecture, Water and Chemistry toward life, Olympiades Regionales des Chimie 2012, 14 Mars 2012, Lycee Mermoz Montpellier.

21. M Barboiu, Plenary Lecture, Dynamic Interactive Systems-toward natural selection of functions, Symposium “Open Problems in Systems Chemistry”, Montpellier, 23-25 01 2012.

22. M. Barboiu, Communication, B Dynamic hybrid materials for constitutional self-instructed membranes, MRS Meeting, Symposium NN San Francisco, USA, 1-5 April, 2013.

23. M. Barboiu, Communication Biomimetic hybrid membrane systems-toward natural selection of functions, MRS Meeting, Sympsium PP San Francisco, USA, 1-5 April, 2013.

24. Y.-X. Shen, E. Licsandru, M. Barboiu, M. Kumar, Poster, Functional reconstitution and characterization artificial water channels for desalination. American Chemical Society Fall Conference, Indianapolis, IN, September 8-12, 2013

25. Y.-X. Shen, E. Licsandru, M. Barboiu, M. Kumar, Poster Functional reconstitution and characterization artificial water channels for desalination. Association of Environmental Engineering and Science Professors Conference, Golden, CO, July 14th-16th, 2013.

26. Y. Le Duc, M. Michau, A. Gilles, V. Gence, Y.-M. Legrand, A.van der Lee, S. Tingry, M. Barboiu, Poster Imidazole I-quartet water and proton dipolar channels, 7 th International Conference on Macrocyclic and Supramolecular Chemistry, Washington DC, USA, 7-11 July, 2013.

27. Y.-X. Shen, E. Licsandru, M. Barboiu, M. Kumar, Poster Functional reconstitution and characterization artificial water channels for desalination. North American Membrane Society Conference, Boise, ID, June 8-12, 2013.

28. G. Nasr, T. Macron, M. Barboiu, Poster Rubbery Organic Frameworks-ROFs-Tuning the gaz-diffusion through dynameric membranes, 47th EUCHEMS Conference on stereochemistry, Brunnen, Switzerland, 28 april-5 May, 2013.

29. Yann Le Duc, Mathieu Michau, Arnaud Gilles, Valerie Gence, Yves-Marie Legrand, Arie van der Lee, Sophie Tingry, Mihail Barboiu, Poster Imidazole I-quartet water and proton dipolar channels, 46th EUCHEMS Conference on stereochemistry, Brunnen, Switzerland, 29 april-6 May, 2012.

30. Participation in the ERC Grantees Conference “Frontier Research in Chemistry” - November 22-24, 2012 - Strasbourg - France

31. Hu, L.; Schaufelberger, F.; Zhang, Y.; Ramström, O. Efficient Asymmetric Synthesis of Lamivudine and its enantiomer via Enzymatic Dynamic Kinetic Resolution. 246th ACS National Meeting & Exposition; Sep 8-12, Indianapolis, IN, USA, 2013.

32. Kong, N.; Shimpi, M.; Yan, M.; Ramström, O. Synthesis of Oligomannan Epitopes for Nanoparticle Functionalization and Cyanovirin-N Binding Evaluation. 245th ACS National Meeting & Exposition; April 7-11, New Orleans, LA, 2013.

33. Thota, N.; Xie, S.; Matei, E.; Gronenborn, A. M.; Yan, M.; Ramström, O. Synthesis of Oligomannan Epitopes for Nanoparticle Functionalization and Cyanovirin-N Binding Evaluation. 245th ACS National Meeting & Exposition; April 7-11, New Orleans, LA, USA, 2013.

34. Zhang, Y.; Jayawardena, S.; Yan, M.; Ramström, O. Lipase Pattern Recognition Through Transformation of Dynamic Hemithioacetal Systems. ISMSC-8: International Symposium on Macrocyclic and Supramolecular Chemistry; Jul 7-11, Arlington, VA, USA, 2013.

35. Zhou, J.; Robles, N. B.; Zhou, Q.; Ramström, O.; Yan, M. Dually Functionalized TEMPO-oxidized Chitin Nanocrystals for Biorecognition Applications. 246th ACS National Meeting & Exposition; Sep 8-12, Indianapolis, IN, USA, 2013.

36. Hu, L.; Zhang, Y.; Ramström, O. Lipase-Catalyzed Dynamic Kinetic Resolution of Novel Heterocycles. The Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12); Nov 12-16, Kyoto, Japan, 2012.

37. Hu, L.; Zhang, Y.; Thota, N.; Ramström, O. Lipase-Catalyzed Dynamic Kinetic Resolution of Novel Heterocycles. 23rd Swedish National Meeting in Organic Chemistry (Organikerdagarna); June 12-15, Göteborg, Sweden, 2012.

38. Neranon, K.; Ramström, O. Assembly of Synthetic Capsids. From Molecules to Materials - Advances and Challenges; July 15-16, Rehovot, Israel, 2012.

39. Ramström, O. Dynamic Systems for Selection, Resolution and Transformation Processes. International Conference on Chemistry for Health; Athens, Sep 9-14, Greece, 2012.

40. Ramström, O. Synthesis and applications of glyconanomaterials. 26th International Carbohydrate Symposium; Jul 22-27, Madrid, Spain, 2012.

41. Ramström, O. Catalytic Promiscuity and Dynamic Systems. Open Problems in Systems Chemistry; Jan 23-24, Montpellier, France, 2012.

42. Zhang, Y.; Sakulsombat, M.; Shuai, Q.; Ramström, O. Lipase-Catalyzed Dynamic Systemic Resolution. 23rd Swedish National Meeting in Organic Chemistry (Organikerdagarna); June 12-15, Göteborg, Sweden, 2012.

43. Zhang, Y.; Sakulsombat, M.; Vongvilai, P.; Hu, L.; Ramström, O. Lipase-mediated dynamic systemic resolution based on single or double reversible reactions. 244th ACS National Meeting & Exposition; American Chemical Society: Aug 19-23, Philadelphia, PA, USA, 2012; p. ORGN–452.

44. Zhou, J.; Robles, N. B.; Kong, N.; Xie, S.; Zhou, Q.; Yan, M.; Ramström, O. Dually Functionalized TEMPO-oxidized Chitin Nanocrystals for Biorecognition Applications. 23rd Swedish National Meeting in Organic Chemistry (Organikerdagarna); June 12-15, Göteborg, Sweden, 2012.

45. Zhang, Y.; Hu, L.; Ramström, O. Dynamic Systems for Selection and Transformation Processes, Supramolecular Approaches in Systems Chemistry, Dec 15-17, 2011, Strasbourg, France.

46. J.J. Barbero, Workshop of the ESF COST project MultiGlycoNano CM1102, Pragues.

47. J.J. Barbero, Conference: “Glycofullerenes as antiadhesive molecules and glycosyltransferase inhibitors” April 2013,

48. J.J. Barbero, 10th Carbohydrate Bioingeneering Meeting, Pragues. “The inhibition of UDP-galactopyranose Mutase by UDP-galactofuranose analogues” April 2013,

49. J.J. Barbero, IVth Spanish Maroccoan Symposium on Organic Chemistry, Almería, Sept 2012

50. J.J. Barbero, III Iberian Carbohydrate Symposium, Vila-Real, Portugal, Sept 2011

51. J.J. Barbero, Glycosciences in the International Year of Chemistry, ESF, Lisbon, Portugal, Sept 2011

52. J.J. Barbero, Posttranslational Modifications of Proteins, Taipei, Taiwan, Nov 2011

53. J.J. Barbero, Valencia Fluorine Days, Valencia, May 2012

54. J.J. Barbero, COST meeting on bacterial diseases, Napoli, June 2012

55. J.J. Barbero, International Leipzig NMR Symposium, Leipzig, June 2012

56. J.J. Barbero, Workshop on Molecular infections form the Chemistry Perspective. Madrid, Jan 2013

57. J.J. Barbero, Workshop on NMR theories and Applications for Proteins. Ratchasima, Thailand, March 2013

58. J.J. Barbero, 20th New Orleans Carbohydrate Symposium,New Orleans, April 2013

59. J.J. Barbero, ACS meeting, New Orleans, April 2013

60. J.J. Barbero, EMBO Workshop on “Glycoproteins: From structure to disease” Palma de Mallorca, April 2013

61. J.J. Barbero, NMR meeting, Rio de Janeiro, May 2013

62. J.J. Barbero, ICIQ Summer School, Tarragona, July 2013

63. Stateva, S. R., & Villalobo, A.: Protein O-GlcNAcylation: a regulatory mechanism in signal transduction. Open Problems in Systems Chemistry (DYNANO meeting) Montpellier, France, January 23-24 (2012).

64. Stateva, S. R., & Villalobo, A: Putative O-GlcNAcylation of the human epidermal growth factor receptor (EGFR). DYNANO Meeting. Montecatini, Italy, October 17-19 (2012).

65. Villalobo, A.: Regulation of the epidermal growth factor receptor by the Ca2+/calmodulin complex. Proceedings Conference on ‘Mechanism-Based Natural Product Development’. Abstract 1-0002 p. 29. Whistler Mountain, BC, Canada. September 21-22 (2012). J. Pharm. Pharmaceut. Sci. 16, No. 2 (2013). (invited talk)

66. Villalobo, A.: Grb7 as a novel anti-tumor target as determined by MRI. 1st International Minisimposium on Advances in Inflammation Imaging (Neurodegeneration and Cancer). Madrid, Spain, November 29-30 (2012). (invited talk)

67. Berchtold, M. W., Panina, S., Stateva, S. R., & Villalobo, A.: Testing the function of calmodulin (CaM) in epidermal growth factor signaling using conditional CaM-knockout cells. Keystone Symposium on PI 3-Kinase and Interplay with Other Signaling Pathways (X3). Keystone, Colorado, USA. Abstract X3 1013 p. 75. February 24 – March 1 (2013).

68. Stateva, S. R., & Villalobo, A: Calmodulin interacts with O-GlcNAc transferase. DYNANO meeting. Budapest, Hungary, March 27-29 (2013).

69. Stateva, S. R., & Villalobo, A.: The role of calmodulin in the control of posttranslational modifications of the epidermal growth factor receptor. DYNANO Meeting. Madrid, Spain. 3-5 October (2013).

70. Solís, D. Lectins as biosensors: characterization of structural and ligand-binding features. Open Problems in Systems Chemistry, January 23-26, 2012, Montpellier, France.

71. Campanero-Rhodes, M.A. Designer’ microarrays: versatile tools for glycosciences, Open Problems in Systems Chemistry, January 23-26, 2012, Montpellier, France.

72. Campanero-Rhodes, M.A. Microarrays for the study of pathogen-host interactions, VI Jornadas Científicas del CIBERES, June 28-29, 2012, Madrid, Spain.

73. Kalograiaki, I. Why are there four letters in the genetic alphabet?, 1st Glycopharm meeting, June 5-7, 2013, Dublin, Ireland.

74. Solís, D. Overview of glycan-binding proteins and biological roles of glycan-protein interactions, 1st Glycopharm meeting, June 5-7, 2013, Dublin, Ireland.

75. Kalograiaki, I. Selective recognition of nontypeable Haemophilus influenzae by endogenous galectins, VI Jornadas de Formación del CIBERES, October 17-18, 2013, Bunyola, Mallorca, Spain.

76. Second International Meeting of the International society for Extracellular Vesicles (ISEV), April 17th-20th 2013, Boston: “Gene expression data suggests a crosstalk between extracellular vesicle and TNF signalling in U937 monocytes” T.G.S. Szabo, K.S.T. Szabo, B.G.N. Gyorgy, B.T.N. Tarr, K.P.N. Paloczy, K.E. Eder, S.T. Toth, X.O. Osteikoetxea, A.N. Németh, A.K. Kittel and E.I.B. Buzás

77. Second International Meeting of the International society for Extracellular Vesicles (ISEV), April 17th-20th 2013, Boston: Ex vivo vesiculation is inhibited in acid-citrate dextrose anticoagulant tube enabling the improved assessment of extracellular vesicles. B. Gyorgy, K. Paloczi, A. Kovacs, E. Barabas, G. Beko, K. Varnai, E. Pallinger, K.E. Szabo-Taylor, G.T. Szabo, A.A. Kiss, A. Falus and E.I. Buzas

78. Second International Meeting of the International society for Extracellular Vesicles (ISEV), April 17th-20th 2013, Boston: Extracellular vesicles generated during apoptosis: does the size matter? B. Szántó, K. Pálóczi, A. Kittel, K. Szabó-Taylor, B. György, T.G. Szabó, A. Németh, M. Szente-Pásztói, M. Deli, M. Csete, A. Szalai, A. Falus and W.I. Buzás

79. Second International Meeting of the International society for Extracellular Vesicles (ISEV), April 17th-20th 2013, Boston: The role of EVs in inflammation. Edit Buzás

80. “Inflammatory cytokines and EVs” in Dublin, at the COST European Network on Microvesicles and Exosomes in Health and Disease (ME-HAD), 17th May 2013, WG3 Meeting presented by K.S.T. Szabo

81. 21st February, 2013. TankóBéla Scientific seminar, Debrecen, Hungary. EI Buzás: Extracellular Vesicles (invited presentation)

82. Hungarian Molecular Life Sciences Meeting, Siófok, Hungary, April 5-7, 2013, Edit Buzás: The role of extracellular vesicles in intercellular communication (plenary lecture)

83. 22-23rd March, 2013, Zsórifürd#, Hungary, Advanced immunology course organized by the Hungarian Society of Immunology. EI Buzás: The role of extracellular vesicles in autoimmune inflammation (invited speaker)

84. May 21-24th, 2013, Sümeg, Hungary, 43th Membrane Transport Meeting, Horizontal molecule transfer by means of extracellular vesicles, EI Buzás (invited speaker)

85. Aug 30-Sept 03, 2013. IMPULSE, an EFIS-EJI Symposium: Extracellular vesicles in context of inflammatory diseases (Edit Buzas invited speaker)

86. Aug 30-Sept 03, 2013. IMPULSE, an EFIS-EJI Symposium: Gene expression changes induced by TNF are significantly modulated by the presence of extracellular vesicles (Szabó-Taylor, K.; T. G. Szabó, B. György, B. Tarr, K. Pálóczy, K. Éder, S. Tóth, X. Osteikoetxea, A. Németh, A. Kittel and E. I. Buzás, poster)

87. Sept. 18-20th, 2013, Valencia. European Network on Microvesicles and Exosomes in Health and Disease (ME-HaD COST BM1202) Training School: Extracellular vesicles: implications in biomedicine, Extracellular vesicles in inflamatio (Edit Buzas trainer and invited speaker)

88. Sept 30-Oct 2, 2013: DYNANO-GLYCOPHARM Summer School, Madrid, Extracellular Vesicles, Emerging New Players in Inflammation (Edit Buzas invited speaker)

89. Oct . 4-6, 2013, ISEV Workshop on Isolation and Characterization of Extracellular Vesiclesm Budapest. Purity and EV damage and quality control (Edit Buzas organizing host, oral presentation)

90. Oct. 6-7, 2013. ME-HaD COST BM1202 WG and MC meetings, Budapest (Edit Buzas, organizing host)

91. Oct. 16-18, 2013. 42th Annual Meeting of the Hungarian Immunological Society, Pécs. The role of extracellular vesicles in immunoregulation. (Edit Buzas, invited speaker)

92. Nov 7-9, 2013. Semmelweis Symposium, Budapest. Extracellular vesicles in inflammation (Edit Buzas, invited speaker and organizing host)

93. Nov 7-9, 2013. Semmelweis Symposium, Budapest. Improved circulating microparticle analysis in acid-citrate dextrose (ACD) anticoagulant tube (Edit Buzas, poster)

94. Nov 7-9, 2013. Semmelweis Symposium, Budapest. Characterization of distinct subpopulations of extracellular vesicles based on their morphology and RNA content (Szabó G Tamás, poster)

95. Nov 7-9, 2013. Semmelweis Symposium, Budapest. Synovial fibroblasts of patients with rheumatoid arthritis express the novel hexosaminidase D enzyme (Szente-Pásztói Mária, poster)

96. Mihaela Gheorghiu “Dynamic assessment of Amyloid oligomers – cell membrane interaction by advanced impedance spectroscopy”, XVth International Conference on Electrical Bio-Impedance (ICEBI), 22-25 April 2013, Heilbad Heiligenstadt, Germany

97. Eugen Gheorghiu “Revealing membrane potential by advanced impedance spectroscopy: theoretical and experimental aspects”, XVth International Conference on Electrical Bio-Impedance (ICEBI), 22-25 April 2013, Heilbad , Heiligenstadt, Germany

98. Szilveszter Gaspar „Sensors for in vitro evaluation of nanomaterial toxicity”, The 12th National Seminar on Nanoscience and Nanotechnology, Romanian Academy, 16 May, 2013, Bucharest

99. Mihaela Gheorghiu, Sorin David, Cristina Polonschii, Dumitru Bratu, Eugen Gheorghiu, "Cellular Platforms for assessing the risks pertaining to nanotechnology”, The 12th National Seminar on Nanoscience and Nanotechnology, Romanian Academy, 16 May 2013, Bucharest

100. Eugen Gheorghiu, ”Electro-Plasmonics for analyzing dynamics of biosystems; theoretical and experimental aspects”, 2nd Workshop on "New Opportunities for Interdisciplinary Research in BIO-NANO-SCIENCE", Romanian Academy – Institute of Biology Bucharest 3rd of June , Bucharest

101. Development and applications of optical and electrical biosensing platforms for cells monitoring and detection, E. Gheorghiu DYNANO – GLYCOPHARM Summer School September 30 – October 2, 2013 Biological Research Centre, CSIC, Madrid, Spain

102. 30th International Conference in Advances in the Applications of Monoclonal Antibodies in Clinical Oncology and Symposium on Cancer Stem Cells, 24th-26th June 2013, Mykonos Presentation by Teodor Aastrup: Drugability of receptors: Accessibility of receptors by means of label free cell-based biosensor

103. World Antibody Drug conjugate summit, February 26th-28th, Frankfurt Presentation by Teodor Aastrup: Label-free cell-based assays: A shift towards biological relevance.

 

Individual Publications directly related to the work

1. Y.M. Legrand, M. Barboiu, Self-Assembled Supramolecular Channels: Toward Biomimetic Materials for Directional Translocation, Chem. Rec., 2013, DOI 10.1002/tcr.201300011

2. L. Marin, I. Stoica, M. Mares, V. Dinu, B. C. Simionescu, M. Barboiu, Antifungal vanillin–imino-chitosan biodynameric films. J. Mat. Chem., 2013, 1 (27), 3353-3358. DOI:10.1039/c3tb20558d

3. M. Barboiu and A. Gilles, Acc. Chem. Res., From natural to bio-assisted and biomimetic artificial water channel systems. 2013, 46, doi: 10.1021/ar400025e.

4. Y. Le Duc, A. Gilles, S. Mihai, V. Rouessac, S. Tingry, M. Barboiu, Dynamic constitutional electrodes-toward functional fullerene wires, Chem. Commun., 2013, 49 3667-3669. DOI:10.1039/C3CC41450G

5. E. Mahon, Z. Mouline, M. Silion, A. Gilles, M. Pinteala and M. Barboiu, Multilayer lectin glyconanoparticles architectures for QCM enhanced detection of sugar–protein interaction, Chem. Commun., 2013, 49(29), 3004-3006. DOI: 10.1039/c3cc41074a.

6. F. Dumitru, Y.M. Legrand, M. Barboiu, A. van der Lee, Weak intermolecular hydrogen and halogen interactions in a isomorophous halogen series of pseudoterpyridine ZnII complexes. Acta Cryst. Sect B, 2013, B69, 43-54.

7. A.Gilles, S. Mihai, G. Nasr,E. Mahon, S. Garai, A. Müller, M. Barboiu, Highly selective Li+ ion transport by porous molybdenum-oxide Keplerate- type nanocapsules integrated in a supported liquid membrane. Israel J. Chem., 2013, 53(1-2), 102-107.

8. G. Nasr, A. Gilles, T. Macron, C. Charmette, J. Sanchez, M. Barboiu, Tuning Gas-Diffusion through Dynameric Membranes: Toward Rubbery Organic Frameworks (ROFs)., Israel J. Chem., 2013, 53(1-2), 97-101. DOI: 10.1002/ijch.201200081

9. G. Nasr, T. Macron, A.Gilles, C. Charmette, J. Sanchez, M. Barboiu, Metallodynameric membranes-are metallic ions facilitating the transport of CO2?, Chem. Commun., 2012, 48(94) 11546-11548, DOI:10.1039/C2CC35821B.

10. S. Mihai, J. Dauthier, Y. Le Duc, A. El Mansouri, A. Mehdi, M. Barboiu, Dynamic constitutional hybrid materials- confined guanosine ribbons within mesoporous silica., Eur. J. Inorg. Chem., 2012, 5299-5304. DOI: 10.1002/ejic.201200754

11. F. Dumitru, Y.-M. Legrand, E. Petit, A. van der Lee, M. Barboiu, Self-sorting of metallosupramolecular DCLs via double-level exchange: amplification in solution and solid state modulation, Dalton Trans., 2012, DOI: 10.1039/c2dt31532g.

12. L. Marin, B. Simionescu, M. Barboiu, Imino-Chitosan Biodynamers, Chem. Commun., 2012, 48, 8778-8780. DOI: 10.1039/C2CC34337A.

13. G. Nasr , T. Macron , A. Gilles , Z. Mouline, M. Barboiu, Metallodynameric membranes – toward the constitutional transport of gases, Chem. Commun., 2012, 48, 6827-6829, DOI: 10.1039/C2CC32656F.

14. G. Nasr, T. Macron, A. Gilles, E. Petit, M. Barboiu, Systems membranes – combining the supramolecular and dynamic covalent polymers for gas-selective dynameric membranes, Chem. Commun., 2012, 48, 7398-7400. DOI: 10.1039/C2CC33603K.

15. D. Dumitrescu, Y.M. Legrand, F. Dumitrascu, M. Barboiu, Aminoguanidinium and Diaminoguanidinium As Adaptive Cationic Building Blocks in Guanidinium–Organosulfonatecrystalline Superstructures, Cryst. Growth Des., 2012, 12 (8), 4258-4263, DOI: 10.1021/cg300756g.

16. E. Mahon, T. Aastrup, M. Barboiu, Dynamic nanoplatforms in biosensors and membrane constitutional systems, Topics Curr. Chem., 2012, 322, 139-164. DOI:10.1007/128_2011_199.

17. M. Barboiu, Constitutional Dynamic Chemistry. Preface, Topics Curr. Chem., 2012, 322, IX-X.

18. M. Barboiu, Multistate and phase change selection in constitutional multivalent systems, Topics Curr. Chem., 2012, 322, 33-54. DOI:10.1007/128_2011_196.

19. Hu, L.; Schaufelberger, F.; Zhang, Y.; Ramström, O., Chem. Commun., 2013, 49, 10376–10378.

20. Zhang, Y.; Hu, L.; Ramström, O. In Supramolecular Systems in Biomedical Fields; Schneider, H.-J., Ed.; RSC Publishing: Cambridge, UK, 2013; pp. 397–418.

21. Zhang, Y.; Hu, L.; Ramström, O., Double Parallel Dynamic Resolution Through Lipase-Catalyzed Asymmetric Transformation., Chem. Commun., 2013, 49, 1805-1807.

22. Sakulsombat, M.; Angelin, M.; Caraballo, R.; Ramström, O., A Dynamic Multicomponent Approach for One-Pot Synthesis of 3-Thioisoindolinones., Isr. J. Chem., 2013, 53, 127-132.

23. Wang, X.; Matei, E.; Deng, L.; Koharudin, L.; Gronenborn, A.; Ramström, O., Yan, M., Sensing lectin–glycan interactions using lectin super-microarrays and glycans labeled with dye-doped silica nanoparticles., Biosens. Bioelectron., 2013, 47, 258–264.

24. Wang, X.; Matei, E.; Gronenborn, A.; Ramström, O., Yan, M., Direct Measurement of Glyconanoparticles and Lectin Interactions by Isothermal Titration Calorimetry., Anal. Chem., 2012, 84 4248-4252.

25. Norberg, O.; Lee, I. H.; Aastrup, T.; Yan, M.; Ramström, O., Photogenerated Lectin Sensors Produced by Thiol-Ene/Yne Photo-Click Chemistry in Aqueous Solution., Biosens. Bioelectron., 2012, 34, 51-56.

26. Zhou, X.; Ramström, O.; Dong, H., Organosilicon-Mediated Regioselective Acetylation of Carbohydrates., Chem. Commun., 2012, 48, 5370-5372.

27. Wang, X.; Norberg, O.; Deng, L.; Ramström, O.; Yan, M., Synthesis of Glyconanomaterials via Photo-initiated Coupling Chemistry., ACS Symp. Ser., 2011, 1091, 49-67.

28. Sakulsombat, M.; Zhang, Y.; Ramström, O., Dynamic Asymmetric Hemithioacetal Transformation by Lipase-Catalyzed #-Lactonization: In Situ Tandem Formation of 1,3-Oxathiolan-5-one Derivatives., Chem. Eur. J., 2012, 18, 6129-6132.

29. Deng, L.; Wang, X.; Uppalapati, S.; Norberg, O.; Dong, H.; Joliton, A.; Yan, M.; Ramström, O., Stereocontrolled 1-S-Glycosylation and Comparative Binding Studies of Photoprobe-Thiosaccharide Conjugates with Their O-Linked Analogs., Pure Appl. Chem., 2012, 85, 1789-1801.

30. Wang, X.; Matei, E.; Deng, L.; Ramström, O., Gronenborn, A.; Yan, M., Multivalent Glyconanoparticles with Enhanced Affinity to the Anti-Viral Lectin Cyanovirin-N., Chem. Commun., 2011, 47, 8620-8622.

31. Wang, X.; Ramström, O., Yan, M., Dynamic light scattering as an efficient tool to study glyconanoparticle-lectin interactions., Analyst, 2011, 136, 4174-4178.

32. Sakulsombat, M.; Zhang, Y.; Ramström, O., Dynamic Systemic Resolution., Top. Curr. Chem., 2012, 322, 55-86.

33. Martín-Santamaría, S.; André, S.; Buzamet, E.; Caraballo, R.; Fernández-Cureses, G.; Morando, M.; Ribeiro, J. P.; Ramírez-Gualito, K.; de Pascual-Teresa, B.; Cañada, F. J.; Menéndez, M.; Ramström, O.; Jiménez Barbero, J.; Solís, D.; Gabius, H.-J., Symmetric dithiodigalactoside: characterization of lectin-binding properties by solid-phase and cell inhibition assays, calorimetry, molecular modelling, and NMR spectroscopy and detection of selectivity between a plant toxin and human lectins., Org. Biomol. Chem., 2011, 9, 5445-5455.

34. Norberg, O.; Deng, L.; Aastrup, T.; Yan, M.; Ramström, O., Photo-Click Immobilization on Quartz Crystal Microbalance Sensors for Selective Carbohydrate-Protein Interaction Analyses. Anal. Chem. 2011, 83, 1000-1007.

35. Deng, L.; Norberg, O.; Uppalapati, S.; Yan, M.; Ramström, O., Stereoselective Synthesis of Photoprobe-Conjugated Thio-Carbohydrates for Glycoarray Fabrication and Evaluation of Protein Binding by SPR Imaging., Org. Biomol. Chem., 2011, 9, 3188-3198.

36. A mannosylated pillar[5]arene derivative: chiral information transfer and antiadhesive properties against uropathogenic bacteria” I. Nierengarten, K. Buffet, M. Holler, S. P. Vincent*, J.-F. Nierengarten*, Tetrahedron Lett., 2013, 54, 2398-2402.

37. G. Eppe, L. Dumitrescu, O. Pierrot, T. Li, W. Pan, S.P. Vincent “A novel base induced isomerization gives access to unprecedented E exo-glycals“, Chem. Eur. J.2013, accepted

38. Campanero-Rhodes, M.A., Llobet, E., López-Merino, L., Kalograiaki, I., André, S., Cano, V., Gabius, H.-J., Bengoechea, J.A. and Solís D. Bacteria microarrays as sensitive tool for studying pathogen-host interactions (in preparation).

39. Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive cooperativity. Ermakova E, Miller MC, Nesmelova IV, López-Merino L, Berbís MA, Nesmelov Y, Tkachev YV, Lagartera L, Daragan VA, André S, Cañada FJ, Jiménez-Barbero J, Solís D, Gabius HJ, Mayo KH., Glycobiology., 2013 May;23(5):508-23.

40. Escherichia coli #-galactosidase inhibitors through modifications at the aglyconic moiety: experimental evidence of conformational distortion in the molecular recognition process. Calle L, Roldós V, Cañada FJ, Uhrig ML, Cagnoni AJ, Manzano VE, Varela O, Jiménez-Barbero J.,  Chem. Eur. J., 2013 Mar 25;19(13):4262-70.

41. Molecular recognition of complex-type biantennary N-glycans by protein receptors: a three-dimensional view on epitope selection by NMR. Ardá A, Blasco P, Varón Silva D, Schubert V, André S, Bruix M, Cañada FJ, Gabius HJ, Unverzagt C, Jiménez-Barbero J., 2013 Feb 20;135(7):2667-75.

42. Protein-carbohydrate interactions studied by NMR: from molecular recognition to drug design. Fernández-Alonso MC, Díaz D, Berbis MÁ, Marcelo F, Cañada J, Jiménez-Barbero J., Curr Protein Pept Sci., 2012 Dec;13(8):816-30.

43. Targeting matrix metalloproteinases: design of a bifunctional inhibitor for presentation by tumour-associated galectins. Bartoloni M, Domínguez BE, Dragoni E, Richichi B, Fragai M, André S, Gabius HJ, Ardá A, Luchinat C, Jiménez-Barbero J, Nativi C., Chem. Eur. J., 2013 Feb 4;19(6):1896-902.

44. Carbohydrate-aromatic interactions. Asensio JL, Ardá A, Cañada FJ, Jiménez-Barbero J., Acc Chem Res., 2013 Apr 16;46(4):946-54.

45. Conformational Selection in Glycomimetics: Human Galectin-1 Only Recognizes syn-#-Type Conformations of #-1,3-Linked Lactose and Its C-Glycosyl Derivative. Vidal P, Roldós V, Fernández-Alonso Mdel C, Vauzeilles B, Bleriot Y, Cañada FJ, André S, Gabius HJ,
Jiménez-Barbero J, Espinosa JF, Martín-Santamaría S., Chem. Eur. J., 2013 Oct 18;19(43):14581-90.

46. Interactions of Bacterial Cell Division Protein FtsZ with C8-Substituted Guanine Nucleotide Inhibitors. A Combined NMR, Biochemical and Molecular Modeling Perspective. Marcelo F, Huecas S, Ruiz-Ávila LB, Cañada FJ, Perona A, Poveda A, Martín-Santamaría S, Morreale A, Jiménez-Barbero J, Andreu JM., J. Am. Chem. Soc., 2013 Nov 6;135(44):16418-28.

47. Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.Nieto L, Canales Á, Fernández IS, Santillana E, González-Corrochano R, Redondo-Horcajo M, Cañada FJ, Nieto P, Martín-Lomas M,
Giménez-Gallego G, Jiménez-Barbero J., Chem. biochem., 2013 Sep 23;14(14):1732-44.

48. LI, H., PANINA, S., KAUR, A., RUANO, M. J., SÁNCHEZ-GONZÁLEZ, P., La COUR, J. M., STEPHAN, A., OLESEN, U. H., BERCHTOLD, M. W., and VILLALOBO, A.: Regulation of the ligand-dependent activation of the epidermal growth factor receptor by calmodulin. J., Biol. Chem.,2012, 287, 3273-3281.

49. Van de WOUWER, M., COUZINIÉ, C., SERRANO-PALERO, M., GONZÁLEZ-FERNÁNDEZ, O., GALMÉS-VARELA, C., MENÉNDEZ-ANTOLÍ, P., GRAU, L., & VILLALOBO, A.: Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells. Nitric Oxide, 2012, 26, 182-191.

50. GABIUS, H.-J., Van de WOUWER, M., ANDRÉ, S., & VILLALOBO, A.: Down-regulation of the epidermal growth factor receptor by altering N-glycosylation: emerging role of ß1,4-galactosyltransferases., Anticancer Res., 2012, 32, 1565-1572.

51. PANINA, S., STEPHAN, A., La COUR, J. M., JACOBSEN, K., KALLERUP, L. K., BUMBULEVICIUTE, R., KNUDSEN, K. V. K., SÁNCHEZ-GONZÁLEZ, P., VILLALOBO, A., OLESEN, U. H., & BERCHTOLD, M. W.: Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system., J. Biol. Chem.2012, 287, 18173-18181.

52. GARCÍA-PALMERO, I., & VILLALOBO, A.: Calmodulin regulates the translocation of Grb7 into the nucleus., FEBS Lett., 2012, 586, 1533-1539.

53. GARCÍA-PALMERO, I., LÓPEZ-LARRUBIA, P., CERDÁN, S., & VILLALOBO, A.: Nuclear magnetic resonance imaging of tumor growth and neovasculature performance in vivo reveals Grb7 as a novel antiangiogenic target., NMR Biomed., 2013,  26, 1059-1069.

54. GARCÍA-PALMERO, I., & VILLALOBO, A.: Deletion of the calmodulin-binding domain of Grb7 impairs cell attachment to the extracellular matrix and migration., Biochem. Biophys. Res. Commun.,2013, 436, 271-277 [Corrigendum: Biochem. Biophys. Res. Commun. 2013, 438, 462 ].

55. BERCHTOLD, M. W., & VILLALOBO, A.: The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer., Biochim. Biophys. Acta – Mol. Cell Res., Doi: 10.1016/j.bbamcr.2013.10.021 (accepted in press) (2013).

56. Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes. Crescitelli R, Lässer C, Szabó TG, Kittel A, Eldh M, Dianzani I, Buzás EI, Lötvall J.J, Extracell Vesicles., 2013 Sep 12;2.

57. PLoS One. 2012;7(11):e49726. Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. György B, Szabó TG, Turiák L, Wright M, Herczeg P, Lédeczi Z, Kittel A, Polgár A, Tóth K, Dérfalvi B, Zelenák G, Böröcz I, Carr B, Nagy G, Vékey K, Gay S, Falus A, Buzás EI., Immunol. Lett., 2013 Jan;149(1-2):71-6.

58. The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis. Pásztói M, Sódar B, Misják P, Pálóczi K, Kittel Á, Tóth K, Wellinger K, Géher P, Nagy G, Lakatos T, Falus A, Buzás EI., Immunol Lett., 2013;149(1-2):71-6.

59. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. A position paper. Kenneth W. Witwer, Edit I. Buzás, Lynne T. Bemis, Adriana Bora, Cecilia Lässer, Jan Lötvall, Esther N. Nolte-‘t Hoen, Melissa G. Piper, SaradaSivaraman, Johan Skog, ClotildeThéry, Marca H. Wauben, Fred Hochberg. Journal of Extracellular Vesicles, 2013, 2: 20360.

60. Reduced Inflammatory Threshold Indicates Skin Barrier Defect in Transglutaminase 3 Knockout Mice. Bognar P, Nemeth I, Mayer B, Haluszka D, Wikonkal N, Ostorhazi E, John S, Paulsson M, Smyth N, Pasztoi M, Buzas EI, Szipocs R, Kolonics A, Temesvari E, Karpati S., J Invest Dermatol.2013 Jul 24.

61. Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer. Szabó DR, Baghy K, Szabó PM, Zsippai A, Marczell I, Nagy Z, Varga V, Eder K, Tóth S, Buzás EI, Falus A, Kovalszky I, Patócs A, Rácz K, Igaz P., Cell Mol Life Sci. 2013 Jun 27. [Epub ahead of print]

62. The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis. Misják P, B#sze S, Horváti K, Pásztói M, Pálóczi K, Holub MC, Szakács F, Aradi B, György B, Szabó TG, Nagy G, Glant TT, Mikecz K, Falus A, Buzás EI., Immunol. Lett., 2013 Apr;152(1):25-31.

63. Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK, Llorente A, Lötvall J, Marcilla A, Mincheva-Nilsson L, Nazarenko I, Nieuwland R, Nolte-'t Hoen EN, Pandey A, Patel T, Piper MG, Pluchino S, Prasad TS, Rajendran L, Raposo G, Record M, Reid GE, Sánchez-Madrid F, Schiffelers RM, Siljander P, Stensballe A, Stoorvogel W, Taylor D, Thery C, Valadi H, van Balkom BW, Vázquez J, Vidal M, Wauben MH, Yáñez-Mó M, Zoeller M, Mathivanan S. PLoS Biol. 2012;10(12):e1001450. doi: 10.1371/journal.pbio.1001450. Epub 2012 Dec 18.

64. Antibacterial effect of microvesicles released from human neutrophilic granulocytes.Timár CI, Lorincz AM, Csépányi-Kömi R, Vályi-Nagy A, Nagy G, Buzás EI, Iványi Z, Kittel A, Powell DW, McLeish KR, Ligeti E.Blood. 2013 Jan 17;121(3):510-8. doi: 10.1182/blood-2012-05-431114..

65. [Potential role for microRNAs in inter-individual and inter-species ommunication]. Igaz P, Nagy Z, Vásárhelyi B, Buzás E, Falus A, Rácz K. Orv Hetil. 2012 Oct 21;153(42):1647-50. doi: 10.1556/OH.2012.29463. Review. Hungarian.

66. CD3#-chain expression of human T lymphocytes is regulated by TNF via Src-like adaptor protein-dependent proteasomal degradation. Érsek B, Molnár V, Balogh A, Matkó J, Cope AP, Buzás EI, Falus A, Nagy G., J. Immunol., 2012 Aug 15;189(4):1602-10.

67. Xueming Li, Yuxin Pei, Ruina Zhang, Qi Shuai, Feng Wang, Teodor Aastrup and Zhichao Pei 2013A suspension-cell biosensor for real-time determination of binding kinetics of protein–carbohydrate interactions on cancer cell surfaces, Chem. Comm., 30 July.

68. An artificial primitive mimic of the Gramicidin-A channel, M. Barboiu, Yann Le Duc, Arnaud Gilles, Pierre-André Cazade, Mathieu Michau, Yves Marie Legrand, Arie van der Lee, Benoit Coasne, Paria Parvizi, Joshua Post & T. Files, Nat. Comm., 2014, DOI:10,1038/ncomms 5142.

69. Reversible Native Chemical Ligation: A facil Access to Dynamic Covalent Peptides, Y. Ruff; V. Garavini & N. Giuseppone, J. Am. Chem. Soc, 2014, 136, 6333-6339


Constitutional Dynamic Chemistry

 

We are proud to announce that five of our prestigious DYNANO partners: Jean-Marie Lehn, Mihai Barboiu, Olof Ramström, Nicolas Giuseppone and Teodor Aastrup are co-authors of the just published book : Constitutional Dynamic Chemistry, presenting critical reviews of the present position and future trends in modern chemical research, a very popular field representing an important pillar of the DYNANO project.

 

 

cda_displayimage

Edited M BARBOIU


Topics in Current Chemistry 322
Springer
ISBN 978-3-642-28343-7
317 pages

 

http://www.springer.com/chemistry/organic+chemistry/book/978-3-642-28343-7?changeHeader

 

Constitutional Dynamic Chemistry (CDC) and its application Dynamic Combinatorial Chemistry (DCC) are new evolutional approaches to produce chemical diversity. In contrast to the classical methods, they allow for the simple generation of functional systems amplified from a mixture of inter-exchanging architectures which result from sets of building blocks interacting reversibly. Kinetic or thermodynamic resolution, self-assembly followed by covalent modification, and phase-change processes all shed light on useful strategies to control and create convergence between self-organization and constitutional functions. Such dynamic libraries have special relevance for a very diverse range of applications such as drug-, catalyst-, and material discovery. CDC implements a dynamic molecular/ supramolecular reversible interface between interacting constituents, mediating the structural self-correlation of different domains of generated systems by virtue of their basic constitutional behaviors. The self-assembly of the components controlled by mastering molecular/supramolecular interactions may allow the flow of structural information from molecular level toward nanoscale dimensions. This volume of Topics in Current Chemistry focuses on constitutional methods for understanding and controlling such upscale propagation of structural information. These methods show potential to impose further precise order at the mesoscale and to discover new routes to obtain highly ordered ultradense arrays over macroscopic distances.

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